Obesity and Inflammation
March 21 - 22, 2007
Boston
No webcast recordings are available for this event.
Welcome
W. Allan Walker, M.D.
Conrad Taff Professor of Nutrition; Director, Division of Nutrition, Harvard Medical School
Keynote Address: Obesity and Inflammation: Integration of Metabolic and Immune Responses
Gokhan S. Hotamisligil, M.D., PhD,
James Stevens Simmons Professor of Genetics and Metabolism, Harvard School of Public Health
SESSION I - HUMAN STUDIES
Moderator:
Gokhan S. Hotamisligil, M.D., PhD
Obesity, Inflammation and Metabolic Disease in Humans
Paresh Dandona, M.D., PhD.,
Director, Diabetes - Endocrinology Center of Western New York,
Distinguished Professor in Medicine, State University of New York (SUNY) at Buffalo
Inflammation and Obesity Related Pathologies
Eric Rimm, ScD.,
Associate Professor of Epidemiology and Nutrition,
Harvard School of Public Health
Therapeutic Opportunities Targeting Inflammation in Humans
Allison B. Goldfine, M.D.,
Investigator, Assistant Director, Clinical Research Section, Joslin Diabetes Center
Discussion
SESSION II - MACROPHAGES AND METABOLIC DISEASE
Moderator:
Andrew S. Greenberg, M.D.
Infiltration of Adipose Tissue by Immune Cells in Obesity: Chicken or Egg?
Haiyan Xu, M.D., PhD.,
Assistant Professor of Medicine, Endocrinology Division, Brown University,
Division of Biology and Medicine, Brown Medical Center
Adipocyte Death and Macrophage Infiltration into Adipose Tissue in Obesity
Andrew S. Greenberg, M.D.,
Dr. Robert C. and Veronica Atkins Professorship in Metabolism and Nutrition,
Scientist I and Director, Obesity and Metabolism Laboratory,
Jean Mayer USDA HNRCA, Tufts University
PPARd and Macrophage Responses
Chih-Hao Lee,
Assistant Professor of Genetics and Complex Diseases,
Harvard School of Public Health
Discussion
SESSION III - NEW PATHS INTEGRATING METABOLISM AND INFLAMMATION
Moderator:
Charalabos Pothoulakis, M.D.
Macrophage ER Stress and Atherosclerosis
Ira Tabas, M.D., Ph.D.,
Richard J. Stock Professor and Vice-Chair of Research, Department of Medicine, Columbia University;
Professor of Medicine and Anatomy & Cell Biology, (in Physiology and Cellular Biophysics),
Columbia University
Role of Inflammation in Non-Alcoholic Steatohepatiti
Anna Mae Diehl, M.D.,
Professor of Medicine; Chief, Division of Gastroenterology;
Director, Duke Liver Center, Duke University
Neuropeptides, Mesenteric Fat, and Intestinal Inflammation
Charalabos Pothoulakis, M.D.,
Director, Gastrointestinal Neuropeptide Center;
Professor of Medicine, Harvard Medical School, Division of Gastroenterology,
Beth Israel Deaconess Medical Center
Discussion
SESSION IV - INFLAMMATION AND COMPLICATIONS OF OBESITY
Moderator:
George Blackburn, M.D., Ph.D.
Introduction
George Blackburn, M.D., Ph.D.,
S. Daniel Abraham Associate Professor of Nutrition;
Associate Director, Division of Nutrition, Harvard Medical School
The Role of TLR in Obesity and Diabetes
Jeffrey Flier, M.D.,
Chief Academic Officer, Harvard Faculty Dean for Academic Affairs,
Beth Israel Deaconess Medical Center,
George C. Reisman Professor of Medicine, Harvard Medical School
IKK & NFkB Pathway in Obesity and Diabetes
Steven E. Shoelson, M.D., Ph.D.,
Helen and Morton Adler Chair, Section Head, Cellular & Molecular Physiology, and
Associate Director of Research, Joslin Diabetes Center,
Professor of Medicine, Harvard Medical School
Oxidative Stress in Obesity and Diabetes
Philip E. Scherer, Ph.D.,
Director, Touchstone Diabetes Center, Department of Internal Medicine,
The University of Texas Southwestern Medical Center
Discussion
SESSION V - LESSONS FROM OTHER DISEASE STATES
Moderator:
Glenn Dranoff, M.D.
Inflammation and Cancer
Glenn Dranoff, M.D.,
Associate Professor of Medicine, Harvard Medical School,
Dana-Farber Cancer Institute
Stress, Inflammation and Neurologic Disease
Xandra O. Breakefield, Ph.D.,
Professor, Department of Neurology, Harvard Medical School;
Geneticist (Neurology and Radiology), Massachusetts General Hospital
Leptin as a Proinflammatory Mediator in Inflammatory Bowel Disease
Giarnila Fantuzzi, Ph.D.,
Associate Professor, Department of Human Nutrition,
University of Illinois at Chicago
Discussion
Closing Remarks
W. Allan Walker, M.D.